GRADE POINTS FOR CLINICAL GUIDELINE PANELISTS #3 - CONFIDENCE LEVEL

Yesterday's blog of this mini-series ended with a listing of the overall rating levels for the GRADE approach. The rating levels are:

  • High
  • Moderate
  • Low 
  • Very low

But what does this mean?

The GRADE approach rates your confidence in the body of evidence from High to Very Low. The interpretation of these is as follows:

High = We are very confident that the true effect lies close to the estimate of the effect.

Moderate = We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.

Low = Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect.

Very Low = We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

The GRADE approach moved away from its original phrasing of rating the quality of evidence. Note that this current phrasing represents your overall certainty of how closely the evidence represents the truth.

The terms High, Moderate, Low and Very Low reflect the level of certainty about the evidence.

More to come.

Or read ahead.  GRADE HANDBOOK

TheEvidenceDoc November 10, 2017